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Human Factor XII

Catalogue Number: HXII 1212
Size: 0.5 mg

Purified from fresh frozen human plasma. Human Factor XII is part of the contact activation system. Human Factor XII is a single chain glycoprotein with a molecular weight of approximately 80,000. Once activated, principally from the action of Kallikrein, Factor XII is converted into the active serine protease (Factor a-XIIa) that functions in the in vivo initiation of blood coagulation, fibrinolysis and kinin formation. Human Factor XII has been purified by ion exchange chromatography. Protein purity is determined by SDS-PAGE and activity is determined via clotting assay.

Buffer Composition = 4 mM Sodium Acetate-HCl / 0.15 M NaCl / pH 5.3

Extinction Coefficient (1%) = 14.1

Molecular Weight = 80,000 daltons

 

Supplied LYOPHILIZED. Shipped at ambient temperature.

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